Articles
| Open Access |
https://doi.org/10.37547/ijmsphr/Volume07Issue02-15
The Use of Ozonized Sesame Oil in Complex Treatment of Ulcerative Necrotic Gingivostomatitis
Abstract
Ulcerative necrotizing gingivostomatitis (UNGS) is a severe inflammatory-destructive disease of the oral mucosa characterized by tissue necrosis, severe pain syndrome, intoxication, and impaired general condition. Despite conventional treatment protocols, the disease often demonstrates prolonged clinical course and recurrence.
This study evaluates the effectiveness of ozonated sesame oil in the комплекс treatment of UNGS. The inclusion of ozonated oil in the therapeutic regimen resulted in a significant reduction of inflammatory indices (OHI-S and PMA), accelerated epithelialization of ulcerative-necrotic lesions, and shortened treatment duration.
Keywords
Ulcerative necrotizing gingivostomatitis, ozone therapy, ozonated sesame oil
References
Тахирова К.А., Азимова А.А. Совершенствование комплексного лечения язвенно-некротического гингивостоматита // DUK “O’zbekiston tibbiyot jurnali” — № 2. —(2025) С. 255-260. .
Тахирова К.А.,Кадырбаева А.А.,Эргашев Н.А.,Азимова А.А.. Иммунологические критерии диагностики язвенно-некротического гингивостоматита // DUK “O’zbekiston tibbiyot jurnali” — № 5. —(2025) С. 89-95.
Saini R. Ozone therapy in dentistry: A strategic review. J Nat Sci Biol Med. 2011;2(2):151–153.
Sechi LA, Lezcano I, Nunez N, Espim M, Dupre I, Pinna A, et al. Antibacterial activity of ozonized sunflower oil (Oleozon). J Appl Microbiol. 2001;90(2):279–284.
Huth KC, Jakob FM, Saugel B, Cappello C, Paschos E, Hollweck R, Hickel R, et al. Effect of ozone on oral cells compared with established antimicrobials. Eur J Oral Sci. 2006;114(5):435–440.
Azarpazhooh A, Limeback H. The application of ozone in dentistry: A systematic review. J Dent. 2008;36(2):104–116.
Trombelli L, Farina R, Silva CO, Tatakis DN. Plaque-induced gingivitis: Case definition and diagnostic considerations. J Clin Periodontol. 2018;45(Suppl 20):S44–S67.
Slots J. Periodontal infections: Microbiology and treatment. Periodontol 2000. 2017;75(1):7–13.
Preshaw PM, Alba AL, Herrera D, Jepsen S, Konstantinidis A, Makrilakis K, Taylor R. Periodontitis and systemic diseases. J Clin Periodontol. 2012;39(Suppl 12):S20–S23.
Patel PV. Gingival diseases: Clinical approach to diagnosis and management. Dent Clin North Am. 2014;58(1):1–14.
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Copyright (c) 2026 Takhirova Kamolakhon Abrorovna , Azimova Aziza Abbosovna
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