Cystic lesions of the jaws are a diverse group of pathologies that can present a wide range of clinical, radiological, and histopathological features. These lesions are commonly encountered in clinical practice, and accurate diagnosis is crucial for determining the appropriate management strategies. This study presents a clinicopathological analysis of 322 cases of cystic lesions of the jaws, aiming to identify the most prevalent types, their clinical presentation, and histopathological characteristics. Data were retrospectively collected from patient records, including clinical examination findings, radiographic images, histological reports, and treatment outcomes. The most common cystic lesions observed were odontogenic cysts, with the dentigerous cyst and the keratocystic odontogenic tumor being the most frequently diagnosed subtypes. A significant portion of cases also involved non-odontogenic cysts such as the nasopalatine duct cyst and the traumatic bone cyst. Radiographically, the majority of cysts appeared as well-defined, expansile lesions, often associated with impacted teeth. Histological examination revealed varying degrees of epithelial lining changes, including squamous, columnar, or odontogenic epithelium, which were essential in differentiating the cystic types. The management of these lesions ranged from conservative surgical approaches to more aggressive resection in cases of recurrent or malignant potential. The findings of this study are supported by a review of current literature, highlighting advances in diagnostic techniques, including imaging modalities and molecular studies, which have improved the understanding and treatment outcomes of these lesions. This comprehensive study provides valuable insights into the clinical and pathological features of jaw cysts, emphasizing the importance of accurate diagnosis for optimal management.

Cystic lesions, jaws, odontogenic cysts

Killy HC, Kay LW. An analysis of 471 benign cystic lesions of the jaws. Int Surg 1966;46:540-5.

Shear M, Speight PM. Cysts of the oral and maxillofacial regions; 4th edition. Oxford: Blackwell Munksgaard; 2007.

Barnes L, Eveson JW, Reichart P, et al. World Health Organization Classification of Tumors. Pathology and Genetics of Head and Neck Tumors. Lyon: IARC Press; 2005.

Bodner L, Bar-Ziv J, Kaffe I. Computed tomography of cystic jaw lesions. J Comput Assist Tomogr 1994;18:22-6.

Radden BG, Reade PC. Odontogenic cysts. A review and clinicopathological study of 368 odontogenic cysts. Aust Dent J 1973;18:218-25.

Pechalova PF, Bakardjiv AG, Beltcheva AB. Jaw cysts at children and adolescence: A single-center retrospective study of 152 cases in southern Bulgaria. Med Oral Pathol Oral Cir Bucal 2011; in press.

Kreidler JF, Raubenheimer EJ, van Heerden WF. A retrospective analysis of 367 cystic lesions of the jaws- the Ulm experience. J Craniomaxillofac Surg 1993;21:339-41.

Daley TD, Wysocky GP, Pringle GA. Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surg Oral Med Oral Pathol 1994;77:276-80.

Jones AV, Craig GT, Franklin CD. Range and demographics of odontogenic cysts diagnosed in UK population over 30-year period. J Oral Pathol Med 2006;35:500-7.

Iatro I, Theologie-Lygidakis N, Leventis M. Intraosseous cystic lesions of the jaws in children: A retrospective analysis of 47 consecutive cases. Oral Surg Oral Med Oral Pathol Radiol Endod 2009;107:485-92.

Lustmann J, Shear M. Radicular cysts arising from deciduous teeth. Int J Oral Surg 1985;14:153-61.

Meningaud JP, Oprean N, Pitak-Arnnop P, Bertrand JC. Odontogenic cysts: a clinical study of 695 cases. J Oral Sci 2006;48:59-62.

Jones AV, Franklin CD. An analysis of oral and maxillofacial pathology found in children over a 30-year period. Int J Paed Dent 2006;16:19-30.

Tortorici S, Amodio E, Massenti M, Buzzanca ML, Burruano F, Vitale F. Prevalence and distribution of odontogenic cysts in Sicily: 1986-2005. J Oral Sci 2008;50:15-8.

Abrahams JJ, Oliverio PJ. Odontogenic cysts: improved imaging with a dental CT software program. Am J Neuroradiol 1993;14:367-74.