EXPLORING THE LINK BETWEEN HYPERCHOLESTEROLEMIA AND ATOPIC DERMATITIS: AGE-RELATED DIFFERENCES IN CHOLESTEROL LEVELS AND DISEASE SEVERITY

Abdul Hakeem Mohammed Saeed; Khaled A. Alqfail

doi:10.37547/ijmsphr/Volume05Issue12-06

Authors

Abdul Hakeem Mohammed Saeed

Medical Department, College of Medicine, Najran University, P.O. Box 1988, Najran, 11001, Saudi Arabia
Khaled A. Alqfail

Assistant professor of Radiology, College of Medicine, Najran University, P.O Box 1988, Najran, Saudi Arabia

Keywords

Hypercholesterolemia Atopic Dermatitis Inflammation

Abstract

The association between hypercholesterolemia and atopic dermatitis (AD) remains a subject of increasing clinical interest due to the shared pathways of systemic inflammation. This study examines 70 patients aged 16 to 60 with elevated blood cholesterol levels (220–350 mg/dL) to investigate the relationship between cholesterol levels and AD severity. Patients were stratified into two groups based on age: those under 40 (48 patients) and those over 40 (22 patients). Results revealed that hypercholesterolemia was more prevalent in older patients, while younger patients exhibited more severe forms of AD, ranging from mild eczema to severe atopic dermatitis. The findings suggest that age plays a critical role in the interplay between lipid metabolism and the inflammatory processes underlying AD, highlighting the importance of lipid monitoring in managing AD severity. Further research is needed to elucidate the mechanisms linking hypercholesterolemia and atopic inflammation.

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