Articles | Open Access | https://doi.org/10.37547/ijmsphr/Volume07Issue01-12

Medical And Social Significance Of Obesity In Obstetric Practice

Safarov Aliaskar Tursunovich , Phd, Associate Professor, Tashkent state medical university, Tashkent, Uzbekistan
Tursunkulova Diyora , Master's Resident, Tashkent, Uzbekistan

Abstract

The prevalence of overweight and obesity among women of reproductive age has increased significantly over recent decades and is now recognized as a global public health problem. Obesity during the pre-pregnancy period and gestation is associated with a wide range of obstetric, metabolic, and cardiovascular complications that adversely affect maternal and fetal outcomes. Excess adipose tissue contributes to insulin resistance, chronic low-grade inflammation, endothelial dysfunction, and hormonal imbalance, which increase the risk of miscarriage, gestational diabetes mellitus, hypertensive disorders of pregnancy, preeclampsia, thromboembolic events, and operative delivery. In addition, maternal obesity alters fetal metabolic programming through dysregulation of glucose, lipid, insulin, and leptin metabolism, leading to fetal macrosomia and an increased risk of obesity and metabolic syndrome in offspring later in life. Despite advances in antenatal care, the incidence of pregnancy complications associated with obesity remains high. Current evidence highlights the importance of preconception counseling, weight management, and multidisciplinary monitoring throughout pregnancy to reduce perinatal morbidity and mortality. Further studies focusing on metabolic and endothelial changes in overweight pregnant women are required to optimize preventive and therapeutic strategies.

Keywords

Maternal obesity, Overweight, Pregnancy complications

References

Боровкова Е.И. Ведение беременности у пациенток с избыточным весом и ожирением. Акушерство гинекология репродукция. - 2010. - Т.4. - № 2.

Маматкулов И. А., Сафарова Л. А., Рашидов З. И. К вопросу о тактике лечения гиперпластических процессов эндометрия у женщин оптимального фертильного возраста //Актуальные вопросы современной медицинской науки и здравоохранения: Сборник статей I Международной (71 Всероссийской) научно-практической конференции молодых ученых и студентов, 13-15 апреля 2016 г. Т. 1. – ФГБОУ ВО УГМУ Минздрава России, 2016.

Abdullayeva L. M. et al. OBSTETRIC AND PERINATAL OUTCOMES IN PATIENTS WITH VERIFIED HIV STATUS //JOURNAL OF EDUCATION AND SCIENTIFIC MEDICINE. – 2025. – №. 5.

Aliaskarovna S. L., Tursunovich S. A. Diagnosis Of DIC Syndrome In Severe Complications Of Pregnancy //Stanford Database Library of International Journal of Medical Sciences And Clinical Research. – 2025. – Т. 5. – №. 12. – С. 35-38.

Chung J.G.Y., Taylor R.S., Thompson J.M.D., Anderson N.H.,Dekker G.A., Kenny L.C., McCowan L.M.E. Gestational weight gain and adverse pregnancy outcomes in a nulliparous cohort // European Journal of Obstetrics & Gynecology and Reproductive Biology. - 2013. - №167. - P. 149-153.

Drake A.J., Reynolds R.M. Impact of maternal obesity on offspring obesity and cardiometabolic risk // Reproduction. 2010. Vol. 140. Р. 387-398.

Gu P., Xu A. Interplay between adipose tissue and blood vessels in obesity and vascular dysfunction. Rev Endocr Metab Disord. 2013. Epub aheadofprint.

Thangaratinam S., Rogoziriska E., Jolly K. et al. Interventions to reduce or prevent obesity in pregnant women: a systematic review. Health Technol Assess. 2012 Jul;16(31):III-IV, 1-191.

Safarov A.T, Urinov M. Y, Safarova L.A, Features of pre-gravidar training and management tactics of pregnant women with alimentary-constitutional type of obesity, Journal of reproductive health and uro-nephrology research. 2021, vol. 1, issue 3.

Safarov Aliaskar Tursunovich, Abdullayeva Lagiya Mirzatullayevna, Safarova Lola Aliaskarovna, Assessment of the impact of HIV infection on the course of gestation, childbirth and the postpartum period, Journal of reproductive health and uro-nephrology research 2022, vol. 3, issue 4. pp.65-67 http://dx.doi.org/10.5281/zenodo.7420945

Safarova L. A. et al. HIV INFECTION AS A FACTOR IN THE DEVELOPMENT OF OBSTETRIC AND PERINATAL COMPLICATIONS //Art of Medicine. International Medical Scientific Journal. – 2023. – Т. 3. – №. 1.

Article Statistics

Downloads

Download data is not yet available.

Copyright License

Download Citations

How to Cite

Safarov Aliaskar Tursunovich, & Tursunkulova Diyora. (2026). Medical And Social Significance Of Obesity In Obstetric Practice. International Journal of Medical Science and Public Health Research, 7(01), 65–68. https://doi.org/10.37547/ijmsphr/Volume07Issue01-12