Significant correlations were identified between the Immune-Stress Index (ISI) and the OHI-S, PLI, PMA, and SBI indices (rₛ = 0.59–0.67; p < 0.001), as well as with the level of dental anxiety and negative behavior (rₛ= 0.62–0.66; p < 0.001). At high ISI values, the risk of unfavorable dental outcomes increased by 3.9–5.6 times. ROC analysis confirmed the high prognostic value of ISI (AUC = 0.86). The findings allow ISI to be considered an integral marker for predicting the risk of developing an unfavorable dental status in children with hearing impairment.

Immune-stress index, children with hearing impairment, salivary cortisol

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