Articles | Open Access | https://doi.org/10.37547/ijmsphr/Volume07Issue03-04

Modern Perspectives on The Impact of Comorbidities on The Course of Covid-19 In Children

Rakhmatullaeva Shaxnoza Baxadirovna , Professor of the Department of Infectious Diseases and Pediatric Infectious Diseases, Doctor of Medical Sciences, Tashkent State Medical University, Tashkent, Uzbekistan
Sadullaev Siroj Ernazarovich , Assistant at the Department of Infectious Diseases, Epidemiology, and Phthisiology of the Urgench State Medical Institute, Urgench, Uzbekistan
Qurbonov Bunyod Shavkatovich , Senior Lecturer at Turon University, Karshi, Uzbekistan
Gullieva Nozima Shavkatovna , Trainee teacher of Turon University Karshi, Uzbekistan

Abstract

This article analyzes contemporary scientific literature regarding the impact of comorbidities on the course of COVID-19 in children. Obesity, diabetes mellitus, cardiovascular diseases, chronic lung diseases, neurological disorders, and immunodeficiency states are examined as independent risk factors for a severe course of COVID-19. Pathogenetic mechanisms, including cytokine storm, increased inflammatory markers, and T-cell immunity dysfunction, are described in detail. The article also highlights the clinical significance of MIS-C syndrome, its diagnostic criteria, modern treatment approaches, and vaccination recommendations.

Keywords

COVID-19, comorbidities, diabetes mellitus

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Rakhmatullaeva Shaxnoza Baxadirovna, Sadullaev Siroj Ernazarovich, Qurbonov Bunyod Shavkatovich, & Gullieva Nozima Shavkatovna. (2026). Modern Perspectives on The Impact of Comorbidities on The Course of Covid-19 In Children. International Journal of Medical Science and Public Health Research, 7(03), 21–26. https://doi.org/10.37547/ijmsphr/Volume07Issue03-04