The functional state of the nose have shown a decrease in respiratory function in patients with chronic “ eosinophilic ” polypous rhinosinusitis, that is, nasal patency ( FEF75/MOS75) was - 2 9 , 4 0, 8 ( p<0.001 in relation to the control group ), prolongation of the transport function time ( 36.3±0.86 minutes) (p < 0.001 in relation to the control group), increase in pH ( 7.4 ±0.01) (p <0.001 relative to the control group), prolongation of absorption time (89.9±6.6 minutes) (p<0.01 relative to the control group), as well as increased excretory function (58.4±0.8 mg ) ( p<0.001 relative to the control group ). Patients in both groups showed impaired nasal function , which can hamper the effect of topical medications on the nasal mucosa, which in turn reduces the effectiveness of treatment. This circumstance must be taken into account when treating these patients.

Microbiological research was carried out in the bacteriological laboratory of the III clinic of the Tashkent Medical Academy, a sample was taken from the nasal cavity of 150 patients. At the same time, determination of the sensitivity of the identified microflora to various antibiotics showed that in almost all cases the monoculture and microbial associations were highly sensitive to cephalosporins, sulfonamides and macrolides. However, it should be noted that in patients with “ neutrophilic ” polypous rhinosinusitis, the nasal microflora was revealed as a monoculture, which was highly sensitive to macrolide antibiotics.

Microbial associations, polyp, mucous membrane

Hasanov US, Khaitov OR, Djuraev JA PECULIARITIES OF THE STATE OF HEARING AND CEREBRAL CHEMODYNAMICS IN PATIENTS WITH DEVIATION OF THE NASAL SEPTUM //UZBEKSKIY MEDITSINSKIY JOURNAL. - 2021. - T. 2. – no. 2.

Djuraev JA i dr. RESULT ANALYSIS CHASTOTY RASPREDELENIE POLYMORPHIZMA RS1800895 592C> AV GENE IL10 SREDI BOLNYX S XPRS //Universum: medicine and pharmacology. – 2023. – no. 3 (97). - S. 11-16.

Hasanov US, Djuraev JA, Shaumarov AZ RESULT ANALYSIS CHASTOTY RASPREDELENIE POLYMORPHIZMA A1188C RS3212227 V GENE IL 12B SREDI PATsIENTOV S XPRS, XRS I CONTROLNOY VYBORKE : dis. - 2023.

Hasanov US, Djuraev JA, Shaumarov AZ RESULT ANALYSIS FREQUENCY DISTRIBUTION POLYMORPHIZMA RS1800895 592C> AV GENE IL10 SREDI BOLNYX S XPRS : dis. - 2023.

Hasanov US i dr. Innovative approaches in the treatment of head and neck button anomalies. - 2022.

Rakhimov AA, Hasanov US, Djuraev JA OSOBENNOSTI MICROBIOLOGICHESKOGO PEYZAJA SLIZISTOY OBOLOCHKI NOSA POSLE SIMULTANNYX HURURGICHESKIX OPERATSIVNYX VMEShATELSTV V NOSOVOY POLOSTI //Nauchnye issledovaniya v vyshey skole: new ideas, problems v nedreniya, poisk decision. - 2022. - S. 142-144.

Djuraev JA, Khasanov US RESULTS OF ANALYSIS OF THE FREQUENCY ANALYSIS OF IL4 GENE C589T RS2243250 POLYMORPHISM AMONG PATIENTS WITH CHRONIC POLYPOSIS RHINOSINUSITIS // JOURNAL OF BIOMEDICINE AND PRACTICE. - S. 77.

Djuraev JA Lipofilling method to eliminate deformities of the face and jaw area. - 2022.

Khodjanov Sh. X. i dr. Clinical and morphological characteristics of anthrochanal polyps // Uzbek medical journal. - 2020. - T. 6. – no. 1.

Khamdamovich K. Yo., Djuraev JA, Yusupov Sh. Sh. Comparative analysis of the frequency of the RS1801394 66A>G polymorphism in the MTR gene in patients with post-COVID-19 complications in the maxillofacial region. - 2022.

Khamdamovich K. Yo., Djuraev JA, Yusupov Sh. Sh. Comparative analysis of the frequency of the RS1801133 66A>G polymorphism in the MTHFR gene in patients with post-COVID-19 complications in the maxillofacial region. - 2022.

Hasanov US i dr. Primary and revision rhinoplasty. - 2022.

Khasanov US, Abdullaev UP, Djuraev JA RESULTS OF AUDIOLOGICAL EXAMINATION IN ACUTE SENSONEURAL HEARING LOSS OF DIFFERENT GENESIS //Oriental Journal of Medicine and Pharmacology. - 2022. - T. 2. – no. 1. – S. 24-50.

Zulunov BS et al. The importance of genetic factors in the treatment of chronic polyposis rhinosinusitis //Eurasian Journal of Otorhinolaryngology-Head and Neck Surgery. - 2023. - T. 2. - S. 71-75.

Khasanov US et al. Rezultati analiza frequency raspredelenie polymorphisma rs1800895 592c> av gene IL10 sredi bolnyx s XPRS //Eurasian Journal of Otorhinolaryngology-Head and Neck Surgery. - 2023. - T. 2. - S. 104-108.

Khasanov US et al. RESULTS OF AUDIOMETRICAL INDICATORS OF COCHLEVESTIBULAR DISORDERS IN PATIENTS WITH ARTERIAL HYPERTENSION DISEASE //Oriental Journal of Medicine and Pharmacology. - 2023. - T. 3. – no. 02. – S. 26-36.

Khasanov US, Abdullaev UP, Djuraev JA RESULTS OF AUDIOLOGICAL EXAMINATION IN ACUTE SENSORINEURAL HEARING LOSS OF VARIOUS GENESIS //Oriental Journal of Medicine and Pharmacology. - 2022. - T. 2. – no. 01. – S. 24-50.

Khasanov US et al. Results of prevalence analysis of IL 12b gene a1188c rs3212227 polymorphism among patients with chronic polyposis rhinosinusitis //Eurasian Journal of Otorhinolaryngology-Head and Neck Surgery. - 2023. - T. 2. - S. 109-115.

Boymuradov SA et al. CHARACTERISTICS OF DIAGNOSTIC JOINT INJURIES OF THE FACIAL SKELETAL BONE TAKING INTO ACCOUNT THE HEMOREOLOGICAL CHARACTERISTICS OF BLOOD //Oriental Journal of Medicine and Pharmacology. - 2022. - T. 2. – no. 1. – S. 51-63.

Khasanov US et al. METHOD FOR THE TREATMENT OF EXUDATIVE OTITIS MEDIA IN CHILDREN //Oriental Journal of Medicine and Pharmacology. - 2022. - T. 2. – no. 01. – S. 64-81.

Khakimov AM, Khodjaev AI, Akhundzhanov NA The state of vestibular function in patients with stroke-related disorders in the form of cerebrovascular disorders and background arterial hypertension //Russian Otorhinolaryngology. – 2002. – no. 3. - S. 62.

Akhundjanov N. Sostoyanie ostroty slukha u bolnykh s hypertonicheskoy boleznyu na fone hypotensivnoy therapy //Stomatologiya. - 2015. - T. 1. – no. 3 (61). - S. 47-50.

Makhsitaliev M. et al. The Functional State Of The Mucous Membrane Of The Nasal Cavity And Paranasal Sinuses After Radical And Minimally Invasive Surgical Interventions //The American Journal of Medical Sciences and Pharmaceutical Research. - 2021. - T. 3. – no. 01. – S. 31-40.

Khasanov US et al. A COMPLEX APPROACH TO THE TREATMENT OF ACUTE SENSONEURAL HEARING LOSS OF DIFFERENT GENES //Oriental Journal of Medicine and Pharmacology. - 2023. - T. 3. – no. 02. – S. 14-25.

Khasanov US et al. VESTIBULAR ANALYZER TEST RESULT INDICATORS OF COCHLEOVESTIBULAR DISORDERS ON THE BACKGROUND OF ARTERIAL HYPERTENSION //Oriental Journal of Medicine and Pharmacology. - 2023. - T. 3. – no. 02. – S. 37-44.

Khasanov US, Akhundjanov NA, Djuraev JA DYNAMICS OF HEARING DISORDERS IN PATIENTS WITH ARTERIAL HYPERTENSION UNDER THE INFLUENCE OF HYPOTENSIVE THERAPY //International Journal of Medical Sciences And Clinical Research. - 2022. - T. 2. – no. 10. – S. 16-20.

Khasanov US, Akhundjanov NA, Djuraev JA INFLUENCE OF ANTIHYPERTENSIVE THERAPY ON VESTIBULAR FUNCTION IN PATIENTS WITH ARTERIAL HYPERTENSION //International Scientific and Current Research Conferences. - 2022. - S. 117-119.

Djuraev JA, Sh K., Akhundzhanov NA A MODERN LOOK AT DIAGNOSTICS AND TREATMENT OF OBSTRUCTIVE APNEA SYNDROME IN SLEEP: dis. - Science and Technology Publishing House, 2022.