Generalized periodontitis is one of the most common dental diseases. The problem of effective treatment of periodontal pathology remains relevant. According to statistics, this nosological form ranks second among dental diseases after dental caries. The following distribution among the population is observed: 86% of adults and 65% of children have pathological changes in periodontal tissues. Tooth loss due to periodontal disease is 2–3 times higher than caries. The results of the study showed that the dynamics of changes in the depth of periodontal pockets in the long-term results of treatment were noted in groups where plasma preparations with a high content of platelet-derived growth factors AMK and PRP were used as part of the treatment complex. The use of autoplasma preparations led to a decrease in the rate of bleeding in all study groups, however, a more pronounced anti-inflammatory effect persisted for a longer time in the first group where AMK and PRP were used, which allows us to recommend these drugs in the complex treatment of generalized periodontitis. In the second group with the use of PPP and i-PRF, a trend towards improvement was observed, which makes it possible to recommend the use of these drugs as an option for maintenance therapy in the treatment of generalized periodontitis.

Generalized periodontitis, plasma therapy, platelet-derived growth factors

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